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Soccer linked to extra mind injury past white matter marks

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Soccer linked to extra mind injury past white matter marks

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Indicators of damage to the mind’s white matter known as white matter hyperintensities, as seen on mind scans, could also be tied extra strongly to vascular threat components, mind shrinkage, and different markers of dementia in former deal with soccer gamers than in those that didn’t play soccer, in line with a research printed within the December 20, 2023, on-line subject of Neurology®, the medical journal of the American Academy of Neurology.

Research have proven that athletes uncovered to repetitive head impacts can have elevated white matter hyperintensity burden of their brains. White matter hyperintensities are simply seen on MRI as markers of damage of assorted causes. We all know these markers are extra widespread as individuals age and with medical circumstances resembling hypertension, however these outcomes present preliminary perception that they might be associated to a number of points of mind injury from repetitive head impacts.”


Michael L. Alosco, PhD, research writer of Boston College Chobanian & Avedisian Faculty of Drugs

Alosco stated white matter hyperintensities on mind scans could also be a promising software to review the long-term results of repetitive head impacts. Repetitive head impacts have additionally been related to continual traumatic encephalopathy (CTE), a neurodegenerative illness that can lead to dementia.

The research doesn’t show that repetitive head impacts and white matter hyperintensities trigger different mind modifications. It solely reveals an affiliation.

The research concerned 120 former skilled soccer gamers and 60 former school soccer gamers with a median age of 57. They have been in comparison with 60 males with a median age of 59 who had no signs, didn’t play soccer, and had no historical past of repetitive head impacts or concussion.

The members had mind scans and lumbar punctures to search for biomarkers of neurodegenerative illness and white matter modifications, together with different assessments.

Within the former soccer gamers, a better burden of white matter hyperintensities was related to larger vascular threat components; elevated concentrations of p-tau proteins present in Alzheimer’s illness, CTE, and different neurodegenerative illnesses; extra mind shrinkage and a lower within the integrity of the white matter pathways within the mind.

The connection between white matter hyperintensities and stroke threat was greater than 11 instances stronger in former soccer gamers than in those that didn’t play soccer. For p-tau, the connection was 2.5 instances stronger within the soccer gamers. For a measure of white matter integrity, the connection was practically 4 instances stronger within the former soccer gamers.

“Whereas our analysis beforehand confirmed that former soccer gamers nonetheless have elevated white matter hyperintensity burden after controlling for sleep apnea, alcohol use and excessive ldl cholesterol, it’s nonetheless necessary to think about engaged on modifying these threat components attributable to their results on cognitive issues and different signs,” Alosco stated.

A limitation of the research was that members volunteered to participate, so they might not signify all former soccer gamers. As well as, since solely elite soccer gamers have been included, the outcomes can’t be simply translated to different populations.

The research was supported by the Nationwide Institutes of Well being and Nationwide Institute of Neurological Problems and Stroke.

Supply:

Journal reference:

Ly, M.T., et al. (2023) Affiliation of Vascular Danger Components and CSF and Imaging Biomarkers With White Matter Hyperintensities in Former American Soccer Gamers. Neurology. doi.org/10.1212/WNL.0000000000208030.

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