Home Mental Health Prozac Alternate options to Take into account — Talkspace

Prozac Alternate options to Take into account — Talkspace

Prozac Alternate options to Take into account — Talkspace


Printed on: 30 Nov 2023

Alternatives to ProzacAlternatives to Prozac

Prozac (fluoxetine) is a typical antidepressant within the class of medication generally known as selective serotonin reuptake inhibitors (SSRIs). These medicine work by altering ranges of the neurotransmitter serotonin within the mind to boost temper.

SSRIs like Prozac are the mostly prescribed antidepressants for treating main depressive dysfunction (MDD), panic dysfunction, obsessive-compulsive dysfunction (OCD), and a few others when prescribed. They’ve fewer unintended effects than different antidepressants, however they’re not appropriate for everybody. 

Folks may search for options to Prozac for quite a lot of causes. They might be involved about Prozac unintended effects, need a extra pure strategy to treating their signs, or the drug may simply not work for them. Lately, curiosity in holistic psychological well being remedy has elevated as folks turn into extra prepared to discover pure treatments to deal with varied situations. 
In case you’re all for studying extra about Prozac options, learn on. We’re protecting what it is advisable to find out about various kinds of antidepressant medicine you’ll be able to strive as an alternative and a number of the in style pure treatments out there as we speak. After getting all the data, you’ll be able to discuss to your physician and decide the very best, best remedy plan to your wants and signs.

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Various Drugs to Prozac

Not too long ago, extra folks have turn into all for studying about medicines that may function a Prozac substitute. Luckily, there are quite a few medicine out there to contemplate.

1. Celexa (citalopram)

Celexa, or the generic title citalopram, is one other antidepressant remedy within the selective serotonin reuptake inhibitor class that helps stability temper by growing serotonin ranges within the mind. Earlier than switching from Prozac to Celexa, you need to discuss to your physician about potential opposed results. Important results to pay attention to embrace a hyperlink to coronary heart points and an elevated danger of interactions with different medicine.

  • Situations Celexa can deal with: Celexa primarily treats main depressive dysfunction, however can be used off-label to deal with nervousness and different situations.
  • Widespread unintended effects of Celexa: Some widespread unintended effects folks might expertise are elevated sweating, headache, diarrhea, nausea, insomnia, and fatigue.

2. Cymbalta (duloxetine)

Cymbalta (duloxetine) is likely one of the important options to Prozac for despair and nervousness. It additionally works by altering neurotransmitters linked to temper swings. Notice that Cymbalta is related to hypertension and liver issues if misused.

  • Situations Cymbalta can deal with: FDA-approved makes use of of Cymbalta embrace main depressive dysfunction, generalized nervousness dysfunction (GAD), fibromyalgia, continual musculoskeletal ache, and diabetic neuropathic ache. It’s additionally used off-label to deal with stress urinary incontinence and chemotherapy-induced peripheral neuropathy.
  • Widespread unintended effects of Cymbalta: Widespread Cymbalta unintended effects embrace complications, problem sleeping, blurred imaginative and prescient, constipation or diarrhea, and dry mouth.

3. Lexapro (escitalopram)

Lexapro (escitalopram) is a well-liked different to Prozac. The drug works equally to the others listed right here, but it surely has fewer reported unintended effects that generally make it value contemplating above different options. Curious how this remedy compares to Prozac? Take a look at our comparability of Lexapro vs. Prozac.

  • Situations Lexapro can deal with: Lexapro is used to deal with main depressive dysfunction and generalized nervousness dysfunction. It’s also used off-label to deal with some consuming problems, OCD, PTSD, panic dysfunction, and extra.
  • Widespread unintended effects of Lexapro: Widespread Lexapro unintended effects embrace dry mouth, nausea, hassle sleeping, dizziness, and constipation.

4. Paxil (paroxetine)

Paxil can be within the SSRI class of medication. It impacts chemical ranges within the mind that may be unbalanced in folks with nervousness, despair, and different psychological well being situations. Notice that in comparison with different SSRIs, Paxil has extra reported unintended effects. In case you’re curious how the unintended effects evaluate to Prozac’s unintended effects, take a look at our information on Paxil vs. Prozac.

  • Situations Paxil can deal with: Paxil is FDA-approved to deal with main depressive dysfunction, panic dysfunction, OCD, and a few nervousness problems, together with social nervousness dysfunction and generalized nervousness dysfunction (GAD). It’s additionally used to deal with post-traumatic stress dysfunction (PTSD) and is used off-label for separation nervousness, physique dysmorphic dysfunction, OCD in kids, and extra. 
  • Widespread unintended effects of Paxil: Unwanted effects of Paxil embrace sexual dysfunction, drowsiness, and weight achieve.
Celexa (citalopram) Main depressive dysfunction Headache
Dry mouth 
Elevated sweating
Drug interactions
Issue sleeping (insomnia) 
Sexual unintended effects
Elevated danger of coronary heart points
Cymbalta (duloxetine) Main depressive dysfunction
Generalized nervousness dysfunction
Ache attributable to diabetic neuropathy
Persistent musculoskeletal ache
Lack of urge for food
Dry mouth
Elevated sweating
Lexapro (escitalopram) Main depressive dysfunction
Generalized nervousness dysfunction
Dry mouth
Issue sleeping
Diarrhea or constipation
Sexual dysfunction
Dizziness or drowsiness
Paxil (paroxetine) Despair
Obsessive-compulsive dysfunction
Generalized nervousness dysfunction
Panic dysfunction
Social nervousness dysfunction
Submit-traumatic stress dysfunction
Premenstrual dysphoric dysfunction
Dry mouth
Blurred imaginative and prescient
Sexual dysfunction
Dizziness or drowsiness
Lack of urge for food or upset abdomen
Weight reduction

Pure Alternate options to Prozac

In case you’re searching for pure options to Prozac for despair, nervousness, or one other situation, you may have a number of choices to contemplate. Analysis suggests that some pure treatments and natural dietary supplements could be efficient for some folks. 

5. Holistic approaches 

  • Train: Bodily exercise is a strong temper booster that releases endorphins, the physique’s pure feel-good chemical substances.
  • Daylight and light-weight remedy: Analysis hyperlinks despair signs to low ranges of Vitamin D. Thus, common publicity to daylight can doubtlessly assist some folks with despair. When treating seasonal have an effect on dysfunction (SAD), gentle containers present synthetic gentle that may also be helpful.
  • Food regimen: A wholesome and balanced weight-reduction plan wealthy in complicated carbohydrates, fruits, greens, complete grains, and legumes may assist raise your temper naturally.
  • Sleep: A daily circadian rhythm and well-maintained sleep helps neurotransmitter ranges to remain optimum.

6. Pure dietary supplements

  • St. John’s wort: St. John’s wort has been used for hundreds of years as an natural treatment recognized for its antidepressant properties. Whereas the proof isn’t conclusive, and extra analysis needs to be carried out, some research present that St. John’s may be an efficient strategy to deal with despair in some instances. 
  • Omega-3 fatty acids: Extra analysis is critical, however a meta-analysis of dozens of research discovered that 1000’s of members noticed helpful results of Omega-3s on depressive signs. Extra analysis additionally suggests Omega-3 fatty acids may be helpful as a non-pharmacological remedy for despair and different temper problems. 
  • S-Adenosyl-L-Methionine (SAMe): Analysis means that SAMe may be helpful for despair, though, like so many different pure or holistic dietary supplements, extra analysis is required. Greater than 40 research recommend that SAMe may be efficient in treating depressive signs, however sadly, most of them are short-term research that solely lasted a few weeks. 

7. Remedy

Discuss remedy (often known as psychotherapy) is confirmed to positively influence the result of psychological well being remedy — in reality, as much as 75% of people that search remedy see advantages. 

“Remedy could be as efficient as Prozac in treating signs of despair and nervousness. If signs are delicate, sufferers usually tend to reply effectively to remedy alone.”

Talkspace psychiatrist Dr. Dion Metzger, MD

Numerous research present that when remedy is mixed with remedy, the outcomes are superior to when both remedy is used alone. 

Talkspace is a safe on-line platform that provides handy, inexpensive entry to remedy. Whether or not you wish to mix remedy with different types of remedy otherwise you wish to use it as an alternative choice to Prozac for managing your psychological well being situation, Talkspace makes the method simpler than ever. 

Issues for Switching to a Prozac Various

In case you’re searching for options to Prozac for nervousness, despair, or some other situation, speaking to your physician about all of the implications of creating a change is vital.

Each particular person can react in a different way to remedy and remedy plans. Monitoring how your physique responds when you’ve just lately switched medicines is important. Whereas recognized and customary unintended effects exist for each drug, that doesn’t imply all people will expertise each aspect impact. Make certain to contact your physician in case you have any aspect impact that worsens or is regarding or surprising.

Discuss to your physician about:

  • Your present well being standing
  • Different medicine and dietary supplements you take
  • Potential unintended effects of any new remedy you’re contemplating
  • Efficacy of options

“Because of its lengthy half-life, Prozac doesn’t should be lowered earlier than stopping. Even on the best dose of 80 mg day by day, you’ll be able to cease taking Prozac “chilly turkey,” and the metabolites of the remedy will work their approach out of your system on their very own. It’s vital to know the danger of switching to a Prozac different is that different remedies will not be as efficient as Prozac. This opens the door for signs of despair or nervousness to return inside weeks or months of switching.”

Talkspace psychiatrist Dr. Dion Metzger, MD

Discover the Proper Various with Talkspace 

Discovering the best remedy plan when looking for Prozac options could be an exhausting, daunting expertise — particularly when you’re attempting to do it by yourself. Talkspace’s on-line psychiatry companies supply a handy, inexpensive, simply accessible strategy to get recommendation about remedy and remedy plans that fit your wants and signs. 

Our licensed psychological well being professionals can information you towards higher psychological well being. Whether or not Prozac isn’t working for you and also you wish to take into account a brand new drug, otherwise you’re searching for pure options to deal with your despair, we might help.

Attain out to Talkspace as we speak to be taught extra about options to Prozac that may be efficient for you. 


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  6.  Campbell PD, Miller AM, Woesner ME. Brilliant Mild Remedy: Seasonal Affective Dysfunction and Past. Einstein J Biol Med. 2019;32:E13-E25. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746555/. Accessed September 24, 2023.
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Talkspace articles are written by skilled psychological health-wellness contributors; they’re grounded in scientific analysis and evidence-based practices. Articles are extensively reviewed by our crew of medical consultants (therapists and psychiatrists of varied specialties) to make sure content material is correct and on par with present trade requirements.

Our purpose at Talkspace is to offer probably the most up-to-date, useful, and goal data on psychological health-related subjects so as to assist readers make knowledgeable selections.

Articles include trusted third-party sources which are both instantly linked to within the textual content or listed on the backside to take readers on to the supply.

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