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Oral Science Professional — Oral Science

Oral Science Professional — Oral Science


Just lately, a member of our workforce, Martha Szczepulski (additionally RDH), met with Steve Pardue, Managing Member at Elevate Oral Care, the corporate behind the event of FluoriMax (2.5% Sodium Fluoride Varnish) and Benefit Arrest (Silver Diamine Fluoride).

Here’s a abstract of their dialogue. We hope this can allow you to combine these extremely efficient in-offices caries administration remedies.


Why is there solely 2.5% NaF in FluoriMax?

Research going again to the Nineteen Nineties present that even in a colophony, the fluoride uptake (bioavailability) could be very comparable between 2.5 and 5% formulations. Subsequently, it’s best to make use of the bottom proportion that produces efficient outcomes. (1)


How a lot hydroxyapatite is in FluoriMax?

3%. It’s a supply of calcium and phosphate. Nevertheless, at this proportion there is no such thing as a actual profit to a traditional mouth, and perhaps a miniscule profit to a affected person with xerostomia. True profit is from the sodium fluoride.


How lengthy does FluoriMax stay within the oral cavity?

It stays till it’s eliminated.

Roughly 90% of the uptake is inside the first 4 hours, the following 24 hours as much as 10%.

That is protected because of the small portions being utilized. 1 drop = 0.1mL, so a beneficiant 3 drop dose can be 0.3mL.

In a research by Dr Beltran, printed in JADA in 2000, the blood plasma ranges of fluoride after FluoriMax utility had been lower than a daily toothpaste utility. (2)


What’s dewaxed meals grade shellac?

Shellac is a pure product that’s produced from a resinous secretion discovered on timber, made by a gaggle of bugs referred to as Kerria lacca. The secretion, referred to as lac, is refined into meals grade shellac, amongst different shellac merchandise.

You should have seen shellac because the shiny coating on an Advil or a Chicklet. 


The place ought to I apply FluoriMax?

The advice is to use to the buccal surfaces in a skinny layer the place it acts as a reservoir. This reservoir works finest as a skinny layer. A thick layer is much less bioavailable and is extra prone to slough off and be swallowed. A skinny layer is extra snug and extra bioavailable.

FluoriMax could be utilized on a lesion or close to a lesion – the fluoride ions can be transported by way of saliva into the lesion regardless.

For optimum uptake, particularly in sufferers with xerostomia, be sure that to use to enamel in shut proximity to the submandibular glands (buccal and lingual sextant 5). This saliva is extra liquid and facilitates fluoride ion transportation. Close to the parotid glands can be good, however this saliva is usually extra ropey and doesn’t facilitate transport in addition to the extra liquid saliva from the submandibular glands.

In extreme xerostomia, sipping a glass of water over the hour after the appliance would assist enhance fluoride uptake – this would supply the mandatory water to help in fluoride ion transportation.


Is there a distinction within the particle dimension of FluoriMax fluoride?

Sure. Typical fluoride particles are within the vary of 150 microns (until the producer mills them first). FluoriMax has micronized particles – the fluoride particles are milled and sifted to fifteen microns and smaller. That is achieved for 2 causes. With smaller particles there may be extra floor space, so due to this fact better bioavailability. Secondly, smaller particles keep in suspension longer (though it’s at all times advisable to shake the bottle earlier than utility to realize an excellent distribution of particles in suspension earlier than shelling out)


Are there any substances that sufferers might have an antagonistic impact to within the FluoriMax?

To our information no. Some folks declare a response to shellac, however this has not been substantiated by scientific literature.


What are excessive depth remedies with FluoriMax?

These are 3 purposes in 5-7 days. This has been achieved in outreach work in different international locations to maximise mineralization in a brief time period publicity with no followup out there.


What are suggestions for getting the perfect out of the product utility and preserving the bottle clear?

All the time shake the bottle 10-15 seconds – lower than that and you could not get the optimum suspension and consistency. FluoriMax is runnier than standard colophony varnish and that could be a good factor as a result of it spreads very skinny and requires much less product.

All the time dispense with the bottle vertical. If the applicator tip will get sticky, wipe off extra with alcohol. If the dispenser is basically clogged, you may take away the cap and rinse with water. If the orifice is plugged, you may open it with a pin. You can even ask for extra shelling out caps from Oral Science. 



Ought to I apply FluoriMax after making use of Benefit Arrest?

There are two methods to use Benefit Arrest. You may apply and permit to air dry for 60 sec. Or you may apply and instantly place a layer of FluoriMax over the AA to seal it in and permit for max penetration. The second measure is finest to make use of in conditions of low affected person compliance. It’s going to additionally make the aftertaste much less metallic. 

It’s unknown whether it is superior to use FluoriMax over Benefit Arrest however it might enhance arrest price.


Is Benefit Arrest protected for gentle tissues (subg and sophistication V purposes)?

Benefit Arrest has a pH of 10 which suggests it’s not caustic to sound gentle tissues. It’s going to dry and blanche tissue briefly, however this isn’t dangerous or painful. 

Benefit Arrest will trigger irritation in wounded tissue. It’s not dangerous however could be delicate. Software of Benefit Arrest shouldn’t be advisable in a case of ulcerative gingivitis if the appliance would contact gentle tissue.


What about inserting Benefit Arrest in deep lesions?

Benefit Arrest will penetrate 2-2.5mm into tooth construction – penetration varies in every tooth and lesion.

Benefit Arrest could be utilized in all carious lesions as much as and together with oblique pulp capping. Direct pulp cap is contraindicated. If there is no such thing as a proof of pulpal involvement or publicity (equivalent to drainage or fistulas), Benefit Arrest could be utilized. When it’s positioned close to pulp, it’ll encourage pulp to shrink. Silver can go into the pulp in oblique pulp cap, however this isn’t detrimental to the pulp or tooth. 


What occurs after I use Benefit Arrest then instantly place a glass ionomer restorative cement?

For those who apply Benefit Arrest and wish to do an instantaneous GI placement:

Apply it as regular, then rinse and dry (don’t dessicate). You may place the GI however some silver can be drawn into the GI, so staining of the GI will happen. That is solely an esthetic concern. It doesn’t lower the bond energy. For optimum bond energy, a polyacrylic acid could also be utilized both earlier than or after the Benefit Arrest (then rinse and dry, don’t dessicate) for max bond energy. If utilizing polyacrylic acid step, you could discover a slight foam on utility of the acid and that is regular.


Easy methods to keep away from GI staining with direct placement of GI (no tooth construction polish or removing)?

To keep away from staining, it’s a two-appointment course of. On first day, apply Benefit Arrest as regular. After 24-72 hours (longer is healthier), place the GI restorative as traditional. This method is known as the two day SMART (Silver Modified Atraumatic Resin Method).


Easy methods to keep away from staining with mild treatment merchandise?

Please notice: Mild curing will “activate” stain of all Benefit Arrest, whether or not it’s on sound or decayed tooth construction. Useful methods to keep away from staining are:

After placement of Benefit Arrest, do a 2-3 second mild treatment to look at if Benefit Arrest has stained an esthetic space, then polish that away. Then you may proceed with restoration. Just a few further issues to contemplate:

  • An opaque GI or resin base can be utilized on the base of the restoration to masks gray tooth construction. Translucent composite might present extra gray by it. 
  • In bonding programs referred to as “Self etch” the place the etch, prime and bond are in a single bottle, the bond is weaker than in non self etch programs. There’s nonetheless bond energy however you could not wish to use this in excessive compression areas, and many others.


How regularly ought to Benefit Arrest be utilized?

Contemplate your affected person habits and assess the hardness of the lesion.

Sufferers with poor oral hygiene and excessive consumption of cariogenic meals may have indefinite reapplication of Benefit Arrest each 3-6 months.

Sufferers with good oral hygiene and low to average consumption of cariogenic meals ought to have a minimum of two purposes. Then reassess the lesion and contemplate making use of each 6 months or yearly to take care of arrest.


How a lot of the lesion is arrested with the appliance?

The primary utility can arrest 70-75% of the lesion. The second utility can arrest 90-95% of the lesion. (2016 research)


Do you’ll want to rinse or not rinse after Benefit Arrest placement?

Both is ok. If no rinse, you could wish to blot web site after placement to soak up extra SDF (to reduce style)


“I heard RivaStar doesn’t stain. Why ought to I exploit Benefit Arrest?”

Information about RivaStar vs Benefit Arrest:

RivaStar has a pH of 13 – it’s caustic to gentle tissues and mustn’t contact gentle tissue. AA has a pH of 10, which isn’t caustic. It might briefly dry and blanche tissue however it’s not dangerous to the tissue. 

RivaStar value per utility is 2-3 occasions that of Benefit Arrest. 

RivaStar is marketed for use underneath GI class I restorations. On this utility, it is not going to stain as a result of it’s primarily sealed in and the product was simply positioned on the ground of the restoration. Nevertheless, if SDF and KI are used alone, or the margins of the restoration comprise SDF and KI, the KI will scale back and decelerate the staining, but it surely doesn’t inhibit the staining. The staining will possible present up inside a month. 

Lastly, when SDF stands alone, it’s a very efficient caries inhibition agent. When SDF and KI are mixed, there may be an virtually half lower in effectivity. Caries inhibition is considerably much less within the presence of SDF and KI mixed. (3)


My conclusion

FluoriMax supplies the identical safety as a traditional varnish, however with a number of main benefits: Elevated bioavailability, which suggests decrease proportion of fluoride is required. The applying is simple, product is skinny and nice, and sufferers can eat and drink straight away. Sufferers which have beforehand stated “no” to varnish love FluoriMax.

Benefit Arrest is a minimally invasive intervention that’s broadly utilized in pediatric and geriatric care. Whereas it is very important inform sufferers and caregivers in regards to the lesion altering colour, I discover affected person acceptance is excessive.  Many caregivers of susceptible sufferers and folks with monetary obstacles are relieved when they’re given an reasonably priced, non-invasive choice that can arrest decay.

For dental hygienists which might be inserting GIs, most restorations with SDF plus KI will inevitably flip darkish, a minimum of across the edges. Utilizing SDF with KI alone will flip darkish over time, and the caries arrest properties are considerably diminished within the presence of KI. And lastly, any lesions which might be subg or on the gingival margin can’t be sufficiently remoted for gentle tissue safety. You might have to cost extra for SDF and KI to recuperate product value. 



1. Seppä L, Results of sodium fluoride concentrations on enamel remineralization in vitro. Scand J Dent Res 1988;96:304-309.

2. Beltrán-Aguilar ED, Goldstein JW, Lockwood SA. Fluoride varnishes. A assessment of their medical use, cariostatic mechanism, efficacy and security. J Am Dent Assoc. 2000 Could;131(5):589-96. doi: 10.14219/jada.archive.2000.0232. PMID: 10832252.

3. Zhao IS, Mei ML, Burrow MF, Lo EC, Chu CH. Impact of Silver Diamine Fluoride and Potassium Iodide Remedy on Secondary Caries Prevention and Tooth Discolouration in Cervical Glass Ionomer Cement Restoration. Int J Mol Sci. 2017 Feb 6;18(2):340. doi: 10.3390/ijms18020340. PMID: 28178188; PMCID: PMC5343875.



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